Tdrd6 is required for spermiogenesis, chromatoid body architecture, and regulation of miRNA expression.

Vasileva A, Tiedau D, Firooznia A, Müller-Reichert T, Jessberger R

Chromatoid bodies (CBs) are characteristic spermatid organelles, which were suggested to function in RNA storage and small RNA processing but whose functions remain largely unknown. CB components include Mili, Miwi, and Tudor domain proteins such as Tdrd6, whose contribution to CB structure and function is elusive.