Biopolis Dresden Imaging Platform

Fission yeast does not age under favorable conditions, but does so after stress.

Coelho M, Dereli A, Haese A, Kühn S, Malinovska L, DeSantis ME, Shorter J, Alberti S, Gross T, Tolić-Nørrelykke IM.

Many unicellular organisms age: as time passes, they divide more slowly and ultimately die. In budding yeast, asymmetric segregation of cellular damage results in aging mother cells and rejuvenated daughters. We hypothesize that the organisms in which this asymmetry is lacking, or can be modulated, may not undergo aging.

GA. taken from Coelho et al, 2013.
  • Curr. Biol. 2013 Oct 7;23(19):1844-52
  • 2013
  • Cell Biology
  • 24035542
  • PubMed

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