Biopolis Dresden Imaging Platform

Changes in morphology and function of adrenal cortex in mice fed a high-fat diet.

Swierczynska MM, Mateska I, Peitzsch M, Bornstein SR, Chavakis T, Eisenhofer G, Lamounier-Zepter V, Eaton S

Obesity is a major risk factor for the development of type 2 diabetes and other debilitating diseases. Obesity and diabetes are intimately linked with altered levels of adrenal steroids. Elevated levels of these hormones induce insulin resistance and cause cardiovascular diseases. The mechanisms underlying obesity-related alterations in adrenal steroids are still not well understood. Here, we investigated how diet-induced obesity affects the morphology and function of the mouse adrenal cortex.

Fig.5 taken from Swierczynska et al, 2015.
  • Int J Obes (Lond) 2015 Feb 12;39(2):321-30
  • 2015
  • Cell Biology
  • 24919565
  • PubMed

Enabled by:

LMF MPI-CBG

Back to list