Gene-Mediated Chemical Communication in Synthetic Protocell Communities.

Tang TD, Cecchi D, Fracasso G, Accardi D, Coutable-Pennarun A, Mansy SS, Perriman AW, Anderson JLR, Mann S

A gene-directed chemical communication pathway between synthetic protocell signaling transmitters (lipid vesicles) and receivers (proteinosomes) was designed, built and tested using a bottom-up modular approach comprising small molecule transcriptional control, cell-free gene expression, porin-directed efflux, substrate signaling, and enzyme cascade-mediated processing.

Journal, Issue, Date: ACS Synth Biol. 2017 Nov 8
Year: 2017
Research Area: Cell Biology
PubMed ID: 29091420
PubMed link: PubMed

Enabled by:

LMF MPI-CBG

Back to list